Introduction Hernia development at the site of a previous colostomy or ileostomy is delayed morbidity associated with enterostomy reversal. Stoma site incisional hernias are a major cause of patient morbidity as they cause abdominal pain, discomfort, impaired quality of life and an increase hospital stay and the number of surgical interventions. Material and Methods We have performed a prospective non-randomized study for assessing Quality of Life Outcomes on a cohort of patients undergoing prophylactic synthetic mesh placement at the time of enterostomy closure. Results In our study performed from March 2021 to February 2023, we enrolled 34 patients undergoing prophylactic synthetic mesh placement at the time of enterostomy closure prospectively and QOL outcomes were assessed at 1, 3, 6 months and 1 year postoperatively using SF 36 and CCS (Carolina Comfort Scale). Mean age of our patients was 46.3 years and 67.6 percent (23/34) of patients were male. Mean SF 36 and CCS scores were decreased in immediate post operative period and at 1 Month but subsequent improvement at 3 months and 6 months with maximum at 1 year was seen. Conclusion Assessment of QOL outcome in preventive hernia surgery in our study reveals significant improvement at 1 year and provides further impetus to growing body of evidence in favor prophylactic mesh placement at time of enterostomy closure.