Purpose: South Sudan is an area of endemic iodine deficiency with a starch-based diet that may not reliably contain animal proteins, seafood, or other natural sources of iodine. The incidence of goitre and other symptoms of IDD can surpass 50% in rural areas with women affected more than men. There is no legislation mandating iodine supplementation of salt in South Sudan. Methodology: A prospective study was undertaken in Juba, South Sudan, to measure the iodine content of salt sold as iodine-fortified in local markets. This included locally-produced and harvested salt, as well as international brands imported to Juba. Results: Salt was purchased from the largest informal market, as well as the largest formal supermarkets in the city. All were labeled and sold as “iodised” or “iodated.” These were tested utilising validated methods sensitive to iodine concentrations as low as 0.2g/mL. Eleven international brands were examined, plus one locally-sourced Sudanese sample. Five brands originated from the UAE, three from Kenya, and one each from the United States, Australia, and Lebanon. Conclusion: The locally-produced salt did not contain detectable iodine, nor did one international brand. The remaining samples did contain detectable iodine supplementation. The cheapest salt was a widely-available Kenyan brand. To our knowledge this is the first chemical analysis of salt marketed as ‘iodised’ in East Africa.