Introduction: Burn injuries often present complex challenges in patient care, especially when early surgical debridement is impractical due to factors such as patient comorbidities, burn size or location. We describe the use and efficacy of Flammacerium, a silver sulfadiazine-cerium nitrate based topical agent, in managing a self-inflicted chemical burn wound in a surgically unfavourable area. Methods: A 67 year-old female was referred to our unit with necrotic full thickness plaques involving 4% TBSA over bilateral inguinal creases extending into her lower abdomen, pubis and labial region. The patient had self-medicated using a combination of baby powder, betamethasone and rectinol creams for intractable pruritis, causing severe chemical burns to this region. Previous attempts at topical treatment by other services were unsuccessful and she was referred to our unit for specialist management. Biopsies demonstrated inflammatory neutrophilic infiltrate with no abnormal histopathology. Given the depth and location of the burns which involved bilateral flexural creases, further surgical debridement and reconstruction was deemed unfavourable with the potential for exposure of femoral triangle contents and predisposition to contractures. She was managed with daily application of Flammacerium and over the course of her hospital admission of 5 weeks, healed without surgical intervention or significant scarring. Discussion: Although use is limited to specialist burns centres with TGA approval for use, Flammacerium remains a useful topical burns dressing adjunct in patients surgically unsuitable for burn wound debridement. In addition to temporising severe burn wounds, Flammacerium prevents the incidence of bacterial colonisation and secondary infection.