This presentation delves into the extraordinary contributions of Sir Geoffrey Keynes, a renowned surgeon whose pioneering spirit left an enduring impact on surgical history. Focused on his ground-breaking work in blood transfusions and revolutionary approaches to breast cancer surgery, Keynes emerges as a luminary who significantly advanced the fields of surgery, oncology, and transfusion medicine. Keynes' work on blood transfusion stands as a milestone in medical history, transforming surgical outcomes through the introduction of stored blood for procedures. This presentation places particular emphasis on Keynes' transformative efforts in breast cancer surgery. His advocacy for breast-conserving techniques including limited mastectomy challenged prevailing norms, and demonstrated a profound understanding of the importance of preserving not only lives but also the quality of life for cancer survivors. His meticulous documentation of outcomes and dedication to refining these techniques paved the way for modern oncoplastic surgery long before the term gained widespread recognition. Beyond his technical contributions, Keynes was a fervent advocate for preserving and documenting the history of surgery. His meticulous efforts in collecting and cataloguing historical surgical instruments, manuscripts, and artefacts have provided invaluable insights into the evolution of surgical practices throughout the centuries. By reflecting on the multifaceted contributions of Sir Geoffrey Keynes, this presentation aims to inspire present-day surgeons to not only push the boundaries of surgical innovation but also appreciate the rich historical tapestry that shapes their profession.