Purpose Infected pancreatic necrosis is a severe complication of acute necrotising pancreatitis, with a high mortality rate. The standard of care is a step-up approach, and minimally invasive techniques for debridement have gained popularity over the severely morbid open necrosectomy, with stent-assisted percutaneous endoscopic necrosectomy (SAPEN) offering a novel approach in Australia. Methodology The case of a 77-year-old man who underwent treatment with SAPEN frames our literature review, using databases PubMed, Scopus, Embase and Medline to review minimally invasive necrosectomy, and evaluate the evidence for SAPEN. Results Other more popular minimally-invasive methods to debride pancreatic necrosis all demonstrate improved morbidity and mortality when compared to open necrosectomy. A 2023 systematic review comparing minimally invasive options found a significantly lower risk ratio for major complications and new onset organ failure in the endoscopic arms. SAPEN has been described in a 23-case series, and a retrospective cohort study, demonstrating no difference in outcomes to a surgical step-up approach, and comparable morbidity and mortality to other minimally invasive methods. Our experience found that having a stent-assisted approach allowed a larger direct access port to the site of necrosis performed under sedation, permitted a greater ability for drainage, as well as a more detailed view of the cavity using larger Fr flexible endoscopes. Conclusion Infected pancreatic necrosis continues to be a high morbidity and mortality event despite improving technology for treatment. Minimally invasive treatment options are superior to open surgery, and the use of SAPEN offers further development of the step-up approach.