Purpose: Peri-operative ulnar neuropathies occur in the anaesthetised patient, are multifactorial in cause and have the potential for sustained disability. In non-orthopaedic patients, this pathology can develop from positioning and padding causing injury to the ulnar nerve, most commonly at the cubital tunnel. Rates of occurrence have plateaued despite wide acceptance of padding and positioning techniques. Methodology: A case of bilateral iatrogenic ulnar nerve neuropathy during bilateral total extraperitoneal inguinal hernia repair performed on a new operating table unfamiliar to theatre staff frames a literature review of iatrogenic, peri-operative ulnar neuropathy in General Surgery patients, using databases PubMed, Scopus, Embase and Medline. Results: Large retrospective studies have demonstrated risk factors of male gender, extremes of body habitus and prolonged hospital stay as risks for persistent peri-operative ulnar neuropathies. Intra-abdominal and pelvic procedures are the most common outside of orthopaedic procedures. Detection usually occurs between 24 hours and 7 days from the procedure, and 90% will resolve within 3 years. While patient factors are not easily modified in the peri-operative setting, padding at the elbow and positioning to avoid cubital tunnel stretch can help avoid this complication. Conclusion: While peri-operative ulnar neuropathy are strongly associated with patient factors, all peri-operative staff can assist in preventing iatrogenic injury with care in positioning and padding the patient.