Purpose Portal vein embolisation (PVE) and hepatic vein embolisation (HVE) are techniques that induce future liver remnant (FLR) growth before hepatectomy in patients with insufficient FLR. Sarcopenia is prevalent in cancer, and can reduce FLR growth leading to poor hepatectomy outcomes. However, body composition changes during operative workup remains unknown. We aim to identify how body composition changes between FLR assessments pre- and post-embolisation. Secondary aims will compare post-operative outcomes of sarcopenic versus non-sarcopenic groups and the effect of sarcopenia on FLR growth. Methodology A retrospective cohort study was conducted using a prospective hepato-pancreato-biliary (HPB) database at Western Health (2017 Jan-2023 Sep). 3D-Lumbar body composition (Skeletal Muscle Index, Visceral Fat Index, Subcutaneous Fat Index) were obtained using an inhouse validated automated artificial intelligence segmentation software on pre- and post-embolisation CT images. Results Of the 401 liver malignancies discussed in the HPB multidisciplinary meetings, 28 patients (22 male, 6 female; Median age 64 years; 11 colorectal liver metastases, 11 cholangiocarcinomas, and 6 hepatocellular carcinomas) underwent PVE and/or HVE. 20 patients proceeded to resection. Changes in body composition post-PVE/HVE will be presented. Post-operative outcomes will be compared between sarcopenic and non-sarcopenic groups, as well as growth rates of FLR. Conclusion Sarcopenia is associated with poor surgical outcomes. Our study investigates the change of body composition pre- and post-PVE/HVE and its association with post-operative outcomes. Future studies investigating prehabilitation strategies to preserve muscle mass should be considered.