Background We share our experience with the use of NovoSorb BTM (biodegradable temporizing matrix) for scalp reconstruction following resection of squamous cell carcinoma (SCC) down to diploe. Case 79 year old male presents with an extensive SCC of the right frontal scalp. The patient underwent resection of the tumor with excision of the outer table using osteotome and immediate application of BTM to the diploe. The BTM is delaminated 6 weeks later and STSG successfully applied. *clinical photographs demonstrating tumor, stages of BTM integration and skin graft* Discussion Histopathology showed poor differentiation, PNI 0.13mm and depth of invasion of 7mm. Margins clear >10mm with no malignancy in the outer table. Post-operative radiotherapy (PORT) is offered to the patient. In the context of significant comorbidities this patient decided not to undergo PORT. His comorbidities included metastatic prostate cancer and lymphoma. The potential need for PORT should be taken into consideration in the decision to use BTM for reconstruction following resection of malignancy. If the patient had decided to proceed with PORT, options would have included proceeding with radiotherapy through the BTM or a transposition flap to provide bulkier coverage over the resection site prior to radiotherapy. Conclusion BTM is a reasonable option for scalp reconstruction following tumor resection, particularly while awaiting formal histopathology results with plan for delayed reconstruction. This can be applied directly to diploe for scalp reconstruction.